Living with advanced dry age-related macular degeneration or Geographic Atrophy

The prevalence of age-related eye diseases including advanced dry age-related macular degeneration or Geographic Atrophy is expected to grow in coming years. Currently this disease affects more than 5 million people worldwide, but the prevalence is expected to double in the next 20 years to more than 10 million.⁹

This site is designed to provide information and support to those affected by advanced dry AMD or Geographic Atrophy, as well as those who care for them.

The following infographic provides key facts and insights about the advanced form of dry age-related macular degeneration or Geographic Atrophy. We have created the infographic in a number of formats in order to ensure we meet the needs of people with visual impairment. The alternative formats can be downloaded below.

Helpful resources & links

References:

1. Gehrs KM, et al. Ann Med. 2006;38(7):450-471.
2. Fleckenstein, M. et al. The progression of geographic atrophy secondary to age-related macular degeneration. Ophthalmology 125, 369–390 (2018).
3. Sivaprasad S, et al. Ophthalmol Ther. 2019;8:115-124
4. Kaszubski P, et al. Ophthalmic Res. 2016;55(4):185-193
5. Boyer, D. S., Schmidt-Erfurth, U., Van Lookeren Campagne, M., Henry, E. C. & Brittain, C. The pathophysiology of geographic atrophy secondary to age-related macular degeneration and the complement pathway as a therapeutic target. Retina 37, 819–835 (2017).
6. Young, R. W. Pathophysiology of age-related macular degeneration. Surv. Ophthalmol. 31, (1987).
7. EURETINA. Retinal Diseases in Europe. PDF file. Accessed Apr. 29, 2021.
   https://www.euretina.org/downloads/EURETINA_Retinal_Diseases.pdf
8. Age-Related Macular Degeneration: Facts & Figures. Bright Focus Foundation. Accessed Apr. 29, 2021. https://www.brightfocus.org/macular/article/age-related-macular-facts-figures
9. Wong WL, et al. Lancet Glob Health. 2014;2:e106-116.
10. What is Geographic Atrophy? Bright Focus Foundation. Accessed Apr. 29, 2021. https://www.brightfocus.org/macular/article/what-geographic-atrophy
11. Ardeljan, D. & Chan, C. C. Aging is not a disease: Distinguishing age-related macular degeneration from aging. Progress in Retinal and Eye Research (2013) doi:10.1016/j.preteyeres.2013.07.003.
12. Bear, M., Connors, B. & Paradiso, M. Neuroscience: Exploring the Brain (Third Edition). Library (Lond). (2006) doi:10.1007/BF02234670.
13. Bonnel, S., Mohand-Said, S. & Sahel, J. A. The aging of the retina. Exp. Gerontol. (2003) doi:10.1016/S0531-5565(03)00093-7.
14. Pennington, K. L. & DeAngelis, M. M. Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors. Eye Vis. 3, (2016).
15. Patel PJ, et al. Clin Ophthalmol. 2020;15-28

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